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Differential role of pannexin-1/ATP/P2X(7) axis in IL-1β release by human monocytes
IL-1β release is integral to the innate immune system. The release of mature IL-1β depends on 2 regulated events: the de novo induction of pro-IL-1β, generally via NF-κB-dependent transduction pathways; and the assembly and activation of the NLRP3 inflammasome. This latter step is reliant on active...
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| 出版年: | FASEB J |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Federation of American Societies for Experimental Biology
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5507675/ https://ncbi.nlm.nih.gov/pubmed/28246166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600256 |
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