Loading...
Five-Membered Ring Peroxide Selectively Initiates Ferroptosis in Cancer Cells
A 1,2-dioxolane (FINO(2)) was identified as a lead compound from a screen of organic peroxides. FINO(2) does not induce apoptosis, but instead initiates ferroptosis, an iron-dependent, oxidative cell death pathway. Few compounds are known to induce primarily ferroptosis. In contrast to the perceived...
Saved in:
| Published in: | ACS Chem Biol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5507670/ https://ncbi.nlm.nih.gov/pubmed/26797166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00900 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|