Apoptosis by [Pt(O,O′-acac)(γ-acac)(DMS)] requires PKC-δ mediated p53 activation in malignant pleural mesothelioma

Mesothelioma cancer cells have epithelioid or sarcomatoid morphology. The worst prognosis is associated with sarcomatoid phenotype and resistance to therapy is affected by cells heterogeneity. We recently showed that in ZL55 mesothelioma cell line of epithelioid origin [Pt(O,O′-acac)(γ-acac)(DMS)] (...

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Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Muscella, Antonella, Vetrugno, Carla, Cossa, Luca Giulio, Antonaci, Giovanna, Barca, Amilcare, De Pascali, Sandra Angelica, Fanizzi, Francesco Paolo, Marsigliante, Santo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507537/
https://ncbi.nlm.nih.gov/pubmed/28704484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181114
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