Different apoptotic effects of [Pt(O,O′-acac)(γ-acac)(DMS)] and cisplatin on normal and cancerous human epithelial breast cells in primary culture

BACKGROUND AND PURPOSE: The aim of this study was to determine whether [platinum (Pt)(O,O′-acetylacetonate (acac))(γ-acac)(dimethylsulphide (DMS))] is differentially cytotoxic in normal and cancer cells, and to measure comparative levels of cytotoxicity compared with cisplatin in the same cells. EXP...

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Detalles Bibliográficos
Publicado en:Br J Pharmacol
Main Authors: Vetrugno, Carla, Muscella, Antonella, Fanizzi, Francesco Paolo, Cossa, Luca Giulio, Migoni, Danilo, De Pascali, Sandra Angelica, Marsigliante, Santo
Formato: Artigo
Idioma:Inglês
Publicado: BlackWell Publishing Ltd 2014
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253461/
https://ncbi.nlm.nih.gov/pubmed/24990093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12831
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