In Vitro and In Vivo Antitumor Activity of [Pt(O,O′-acac)(γ-acac)(DMS)] in Malignant Pleural Mesothelioma

Malignant pleural mesothelioma (MPM) is an aggressive malignancy highly resistant to chemotherapy. There is an urgent need for effective therapy inasmuch as resistance, intrinsic and acquired, to conventional therapies is common. Among Pt(II) antitumor drugs, [Pt(O,O′-acac)(γ-acac)(DMS)] (Ptac2S) ha...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Muscella, Antonella, Vetrugno, Carla, Cossa, Luca Giulio, Antonaci, Giovanna, De Nuccio, Francesco, De Pascali, Sandra Angelica, Fanizzi, Francesco Paolo, Marsigliante, Santo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091852/
https://ncbi.nlm.nih.gov/pubmed/27806086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165154
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