In Vitro and In Vivo Antitumor Activity of [Pt(O,O′-acac)(γ-acac)(DMS)] in Malignant Pleural Mesothelioma

Malignant pleural mesothelioma (MPM) is an aggressive malignancy highly resistant to chemotherapy. There is an urgent need for effective therapy inasmuch as resistance, intrinsic and acquired, to conventional therapies is common. Among Pt(II) antitumor drugs, [Pt(O,O′-acac)(γ-acac)(DMS)] (Ptac2S) ha...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Muscella, Antonella, Vetrugno, Carla, Cossa, Luca Giulio, Antonaci, Giovanna, De Nuccio, Francesco, De Pascali, Sandra Angelica, Fanizzi, Francesco Paolo, Marsigliante, Santo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091852/
https://ncbi.nlm.nih.gov/pubmed/27806086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165154
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