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Position effects influencing intrachromosomal repair of a double-strand break in budding yeast

Repair of a double-strand break (DSB) by an ectopic homologous donor sequence is subject to the three-dimensional arrangement of chromosomes in the nucleus of haploid budding yeast. The data for interchromosomal recombination suggest that searching for homology is accomplished by a random collision...

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Bibliographic Details
Published in:PLoS One
Main Authors: Wang, Ruoxi W., Lee, Cheng-Sheng, Haber, James E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507452/
https://ncbi.nlm.nih.gov/pubmed/28700723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180994
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