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Chromosome position determines the success of double-strand break repair

Repair of a chromosomal double-strand break (DSB) by gene conversion depends on the ability of the broken ends to encounter a donor sequence. To understand how chromosomal location of a target sequence affects DSB repair, we took advantage of genome-wide Hi-C analysis of yeast chromosomes to create...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lee, Cheng-Sheng, Wang, Ruoxi W., Chang, Hsiao-Han, Capurso, Daniel, Segal, Mark R., Haber, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720327/
https://ncbi.nlm.nih.gov/pubmed/26715752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523660113
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