Unexpected effects of azole transporter inhibitors on antifungal susceptibility in Candida glabrata and other pathogenic Candida species

The pathogenic fungus Candida glabrata is often resistant to azole antifungal agents. Drug efflux through azole transporters, such as Cdr1 and Cdr2, is a key mechanism of azole resistance and these genes are under the control of the transcription factor Pdr1. Recently, the monoamine oxidase A (MAO-A...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Nagayoshi, Yohsuke, Miyazaki, Taiga, Shimamura, Shintaro, Nakayama, Hironobu, Minematsu, Asuka, Yamauchi, Shunsuke, Takazono, Takahiro, Nakamura, Shigeki, Yanagihara, Katsunori, Kohno, Shigeru, Mukae, Hiroshi, Izumikawa, Koichi
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507446/
https://ncbi.nlm.nih.gov/pubmed/28700656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180990
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