Roles of Calcineurin and Crz1 in Antifungal Susceptibility and Virulence of Candida glabrata

A Candida glabrata calcineurin mutant exhibited increased susceptibility to both azole antifungal and cell wall-damaging agents and was also attenuated in virulence. Although a mutant lacking the downstream transcription factor Crz1 displayed a cell wall-associated phenotype intermediate to that of...

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Detalhes bibliográficos
Main Authors: Miyazaki, Taiga, Yamauchi, Shunsuke, Inamine, Tatsuo, Nagayoshi, Yosuke, Saijo, Tomomi, Izumikawa, Koichi, Seki, Masafumi, Kakeya, Hiroshi, Yamamoto, Yoshihiro, Yanagihara, Katsunori, Miyazaki, Yoshitsugu, Kohno, Shigeru
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849377/
https://ncbi.nlm.nih.gov/pubmed/20100876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01364-09
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