Unexpected effects of azole transporter inhibitors on antifungal susceptibility in Candida glabrata and other pathogenic Candida species

The pathogenic fungus Candida glabrata is often resistant to azole antifungal agents. Drug efflux through azole transporters, such as Cdr1 and Cdr2, is a key mechanism of azole resistance and these genes are under the control of the transcription factor Pdr1. Recently, the monoamine oxidase A (MAO-A...

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Publicado en:PLoS One
Autores principales: Nagayoshi, Yohsuke, Miyazaki, Taiga, Shimamura, Shintaro, Nakayama, Hironobu, Minematsu, Asuka, Yamauchi, Shunsuke, Takazono, Takahiro, Nakamura, Shigeki, Yanagihara, Katsunori, Kohno, Shigeru, Mukae, Hiroshi, Izumikawa, Koichi
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507446/
https://ncbi.nlm.nih.gov/pubmed/28700656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180990
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