Dengue-2 Vaccine: Viremia and Immune Responses in Rhesus Monkeys

Studies were undertaken in Indian rhesus monkeys (Macaca mulatta) to determine the safety, potency, immunogenicity, and mosquito infectivity of a small-plaque, temperature-sensitive variant of dengue type 2 (DEN-2) virus, a vaccine candidate. Fifteen monkeys were inoculated subcutaneously with the v...

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Bibliographic Details
Main Authors: Scott, Robert McN., Nisalak, Ananda, Eckels, Kenneth H., Tingpalapong, Markpol, Harrison, Venton R., Gould, Douglas J., Chapple, Frank E., Russell, Philip K.
Format: Artigo
Language:Inglês
Published: 1980
Subjects:
Viral Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC550741/
https://ncbi.nlm.nih.gov/pubmed/6766903
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