Randomized, Placebo-Controlled Trial of Nonpegylated and Pegylated Forms of Recombinant Human Alpha Interferon 2a for Suppression of Dengue Virus Viremia in Rhesus Monkeys

Dengue fever and dengue hemorrhagic fever are caused by infection with any one of the four dengue viruses (DVs) and are significant public health burdens throughout the tropics. Higher viremia levels are associated with greater dengue disease severity. A therapeutic intervention to suppress viremia...

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Main Authors: Ajariyakhajorn, C., Mammen, M. P., Endy, T. P., Gettayacamin, M., Nisalak, A., Nimmannitya, S., Libraty, D. H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280153/
https://ncbi.nlm.nih.gov/pubmed/16251289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.11.4508-4514.2005
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