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Talin plays a critical role in the maintenance of the regulatory T cell pool

Talin, a cytoskeletal protein essential in mediating integrin activation, has been previously shown to be involved in the regulation of T cell proliferation and function. Here we describe a role for talin in maintaining the homeostasis and survival of the regulatory T (Treg) cell pool. T cell-specif...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Klann, Jane E., Remedios, Kelly A., Kim, Stephanie H., Metz, Patrick J., Lopez, Justine, Mack, Lauren A., Zheng, Ye, Ginsberg, Mark H., Petrich, Brian G., Chang, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507362/
https://ncbi.nlm.nih.gov/pubmed/28515282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601165
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