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Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance

Podocytes are specialized actin-rich epithelial cells that line the kidney glomerular filtration barrier. The interface between the podocyte and the glomerular basement membrane requires integrins, and defects in either α(3) or β(1) integrin, or the α(3)β(1) ligand laminin result in nephrotic syndro...

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Detalhes bibliográficos
Main Authors: Tian, Xuefei, Kim, Jin Ju, Monkley, Susan M., Gotoh, Nanami, Nandez, Ramiro, Soda, Keita, Inoue, Kazunori, Balkin, Daniel M., Hassan, Hossam, Son, Sung Hyun, Lee, Yashang, Moeckel, Gilbert, Calderwood, David A., Holzman, Lawrence B., Critchley, David R., Zent, Roy, Reiser, Jochen, Ishibe, Shuta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934159/
https://ncbi.nlm.nih.gov/pubmed/24531545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69778
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