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Biologically relevant oxidants cause bound proteins to readily oxidatively crosslink at guanine
Oxidative DNA-protein crosslinks have received less attention than other types of DNA damage and remain as one of the least understood types of oxidative lesion. A model system using Ribonuclease A and a 27-nucleotide DNA was used to determine the propensity of oxidative crosslinking to occur in the...
में बचाया:
| में प्रकाशित: | Chem Res Toxicol |
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| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5507331/ https://ncbi.nlm.nih.gov/pubmed/22216745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200376e |
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