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Developing ICP-MS/MS for the detection and determination of synthetic DNA-protein crosslink models via phosphorus and sulfur detection

Various endogenous and exogenous agents drive the un-directed formation of covalent bonds between proteins and DNA. These complex molecules are of great biological relevance, as can derive in mutations, but are difficult to study because of their heterogeneous chemical properties. New analytical app...

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Detalhes bibliográficos
Publicado no:Anal Bioanal Chem
Main Authors: Gong, Jiawei, Solivio, Morwena J., Merino, Edward J., Caruso, Joseph A., Landero-Figueroa, Julio A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593307/
https://ncbi.nlm.nih.gov/pubmed/25651903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-015-8504-x
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