Cigarette smoke differentially affects IL‐13‐induced gene expression in human airway epithelial cells

Allergic airways inflammation in asthma is characterized by an airway epithelial gene signature composed of POSTN,CLCA1, and SERPINB2. This Th2 gene signature is proposed as a tool to classify patients with asthma into Th2‐high and Th2‐low phenotypes. However, many asthmatics smoke and the effects o...

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Bibliographic Details
Published in:Physiol Rep
Main Authors: Mertens, Tinne C. J., van der Does, Anne M., Kistemaker, Loes E., Ninaber, Dennis K., Taube, Christian, Hiemstra, Pieter S.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506530/
https://ncbi.nlm.nih.gov/pubmed/28701525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13347
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