Muscarinic M(3) receptors on structural cells regulate cigarette smoke-induced neutrophilic airway inflammation in mice

Anticholinergics, blocking the muscarinic M(3) receptor, are effective bronchodilators for patients with chronic obstructive pulmonary disease. Recent evidence from M(3) receptor-deficient mice (M(3)R(−/−)) indicates that M(3) receptors also regulate neutrophilic inflammation in response to cigarett...

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I publikationen:Am J Physiol Lung Cell Mol Physiol
Huvudupphovsmän: Kistemaker, Loes E. M., van Os, Ronald P., Dethmers-Ausema, Albertina, Bos, I. Sophie T., Hylkema, Machteld N., van den Berge, Maarten, Hiemstra, Pieter S., Wess, Jürgen, Meurs, Herman, Kerstjens, Huib A. M., Gosens, Reinoud
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2014
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315453/
https://ncbi.nlm.nih.gov/pubmed/25381025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00259.2014
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