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Pro-inflammatory mechanisms of muscarinic receptor stimulation in airway smooth muscle

BACKGROUND: Acetylcholine, the primary parasympathetic neurotransmitter in the airways, plays an important role in bronchoconstriction and mucus production. Recently, it has been shown that acetylcholine, by acting on muscarinic receptors, is also involved in airway inflammation and remodelling. The...

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Detalhes bibliográficos
Main Authors: Oenema, Tjitske A, Kolahian, Saeed, Nanninga, Janke E, Rieks, Daniëlle, Hiemstra, Pieter S, Zuyderduyn, Suzanne, Halayko, Andrew J, Meurs, Herman, Gosens, Reinoud
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955662/
https://ncbi.nlm.nih.gov/pubmed/20875145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-130
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