Pro-inflammatory mechanisms of muscarinic receptor stimulation in airway smooth muscle

BACKGROUND: Acetylcholine, the primary parasympathetic neurotransmitter in the airways, plays an important role in bronchoconstriction and mucus production. Recently, it has been shown that acetylcholine, by acting on muscarinic receptors, is also involved in airway inflammation and remodelling. The...

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Main Authors: Oenema, Tjitske A, Kolahian, Saeed, Nanninga, Janke E, Rieks, Daniëlle, Hiemstra, Pieter S, Zuyderduyn, Suzanne, Halayko, Andrew J, Meurs, Herman, Gosens, Reinoud
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955662/
https://ncbi.nlm.nih.gov/pubmed/20875145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-130
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