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Anti‐aging drugs reduce hypothalamic inflammation in a sex‐specific manner

Aging leads to hypothalamic inflammation, but does so more slowly in mice whose lifespan has been extended by mutations that affect GH/IGF‐1 signals. Early‐life exposure to GH by injection, or to nutrient restriction in the first 3 weeks of life, also modulate both lifespan and the pace of hypothala...

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Опубликовано в: :Aging Cell
Главные авторы: Sadagurski, Marianna, Cady, Gillian, Miller, Richard A.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506421/
https://ncbi.nlm.nih.gov/pubmed/28544365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12590
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