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Sex-specific brain erythropoietin regulation of mouse metabolism and hypothalamic inflammation

The blood hormone erythropoietin (EPO), upon binding to its receptor (EpoR), modulates high-fat diet–induced (HFD-induced) obesity in mice, improves glucose tolerance, and prevents white adipose tissue inflammation. Transgenic mice with constitutive overexpression of human EPO solely in the brain (T...

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Podrobná bibliografie
Vydáno v:JCI Insight
Hlavní autoři: Dey, Soumyadeep, Cui, Zhenzhong, Gavrilova, Oksana, Zhang, Xiaojie, Gassmann, Max, Noguchi, Constance T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141393/
https://ncbi.nlm.nih.gov/pubmed/32078583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134061
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