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Sex-specific brain erythropoietin regulation of mouse metabolism and hypothalamic inflammation

The blood hormone erythropoietin (EPO), upon binding to its receptor (EpoR), modulates high-fat diet–induced (HFD-induced) obesity in mice, improves glucose tolerance, and prevents white adipose tissue inflammation. Transgenic mice with constitutive overexpression of human EPO solely in the brain (T...

詳細記述

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書誌詳細
出版年:JCI Insight
主要な著者: Dey, Soumyadeep, Cui, Zhenzhong, Gavrilova, Oksana, Zhang, Xiaojie, Gassmann, Max, Noguchi, Constance T.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141393/
https://ncbi.nlm.nih.gov/pubmed/32078583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134061
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