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Sex-specific brain erythropoietin regulation of mouse metabolism and hypothalamic inflammation
The blood hormone erythropoietin (EPO), upon binding to its receptor (EpoR), modulates high-fat diet–induced (HFD-induced) obesity in mice, improves glucose tolerance, and prevents white adipose tissue inflammation. Transgenic mice with constitutive overexpression of human EPO solely in the brain (T...
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| Опубликовано в: : | JCI Insight |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7141393/ https://ncbi.nlm.nih.gov/pubmed/32078583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134061 |
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