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Erythropoietin-Induced Changes in Bone and Bone Marrow in Mouse Models of Diet-Induced Obesity

Obesity remodels bone and increases bone marrow adipocytes (BMAT), which negatively regulate hematopoiesis and bone. Reduced BMAT could restore altered hematopoiesis and bone features. We analyzed the potential of erythropoietin (EPO), the cytokine required for erythropoiesis, to inhibit BMAT in C57...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Suresh, Sukanya, Alvarez, Josue Caban, Dey, Soumyadeep, Noguchi, Constance Tom
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084787/
https://ncbi.nlm.nih.gov/pubmed/32121294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051657
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