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Erythropoietin-Induced Changes in Bone and Bone Marrow in Mouse Models of Diet-Induced Obesity

Obesity remodels bone and increases bone marrow adipocytes (BMAT), which negatively regulate hematopoiesis and bone. Reduced BMAT could restore altered hematopoiesis and bone features. We analyzed the potential of erythropoietin (EPO), the cytokine required for erythropoiesis, to inhibit BMAT in C57...

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Publicat a:Int J Mol Sci
Autors principals: Suresh, Sukanya, Alvarez, Josue Caban, Dey, Soumyadeep, Noguchi, Constance Tom
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084787/
https://ncbi.nlm.nih.gov/pubmed/32121294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051657
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