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Sustained NFκB inhibition improves insulin sensitivity but is detrimental to muscle health

Older adults universally suffer from sarcopenia and approximately 60–70% are diabetic or prediabetic. Nonetheless, the mechanisms underlying these aging‐related metabolic disorders are unknown. NFκB has been implicated in the pathogenesis of several aging‐related pathologies including sarcopenia and...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Zhang, Ning, Valentine, Joseph M., Zhou, You, Li, Mengyao E., Zhang, Yiqiang, Bhattacharya, Arunabh, Walsh, Michael E., Fischer, Katherine E., Austad, Steven N., Osmulski, Pawel, Gaczynska, Maria, Shoelson, Steven E., Van Remmen, Holly, Chen, Hung I., Chen, Yidong, Liang, Hanyu, Musi, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506420/
https://ncbi.nlm.nih.gov/pubmed/28556540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12613
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