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Harnessing Proteasome Dynamics and Allostery in Drug Design
Significance: The proteasome is the essential protease that is responsible for regulated cleavage of the bulk of intracellular proteins. Its central role in cellular physiology has been exploited in therapies against aggressive cancers where proteasome-specific competitive inhibitors that block prot...
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| Publicado no: | Antioxid Redox Signal |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4241894/ https://ncbi.nlm.nih.gov/pubmed/24410482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5816 |
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