eIF2α signaling regulates ischemic osteonecrosis through endoplasmic reticulum stress

Osteonecrosis of the femoral head (ONFH) primarily results from ischemia/hypoxia to the femoral head, and one of the cellular manifestations is the endoplasmic reticulum (ER) stress. To understand possible linkage of ischemic osteonecrosis to the ER stress, a surgery-induced animal model was employe...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Daquan, Zhang, Yunlong, Li, Xinle, Li, Jie, Yang, Shuang, Xing, Xiaoxue, Fan, Guanwei, Yokota, Hiroki, Zhang, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505953/
https://ncbi.nlm.nih.gov/pubmed/28698612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05488-6
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