Mechanical loading mitigates osteoarthritis symptoms by regulating endoplasmic reticulum stress and autophagy

Osteoarthritis (OA) is a disease characterized by cartilage damage and abnormal remodeling of subchondral bone. Our previous study showed that in the early stage of OA, knee loading exerts protective effects by suppressing osteoclastogenesis through Wnt signaling, but little is known about loading e...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Zheng, Weiwei, Li, Xinle, Liu, Daquan, Li, Jie, Yang, Shuang, Gao, Zhe, Wang, Zhaonan, Yokota, Hiroki, Zhang, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404578/
https://ncbi.nlm.nih.gov/pubmed/30485126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801851R
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