Frontline Science: Myeloid cell-specific deletion of Cebpb decreases sepsis-induced immunosuppression in mice

Sepsis inflammation accelerates myeloid cell generation to compensate for rapid mobilization of the myeloid progenitors from bone marrow. This inflammation-driven myelopoiesis, however, generates myeloid progenitors with immunosuppressive functions that are unable to differentiate into mature, innat...

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Vydáno v:J Leukoc Biol
Hlavní autoři: McPeak, Melissa B., Youssef, Dima, Williams, Danielle A., Pritchett, Christopher L., Yao, Zhi Q., McCall, Charles E., El Gazzar, Mohamed
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Leukocyte Biology 2017
Témata:
Spotlight on Leading Edge Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505744/
https://ncbi.nlm.nih.gov/pubmed/28476751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4HI1216-537R
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