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Low active loading of cargo into engineered extracellular vesicles results in inefficient miRNA mimic delivery
Extracellular vesicles (EVs) hold great potential as novel systems for nucleic acid delivery due to their natural composition. Our goal was to load EVs with microRNA that are synthesized by the cells that produce the EVs. HEK293T cells were engineered to produce EVs expressing a lysosomal associated...
Zapisane w:
| Wydane w: | J Extracell Vesicles |
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| Główni autorzy: | , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5505005/ https://ncbi.nlm.nih.gov/pubmed/28717424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2017.1333882 |
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