High Frequency Components of Hemodynamic Shear Stress Profiles are a Major Determinant of Shear-Mediated Platelet Activation in Therapeutic Blood Recirculating Devices

We systematically analyzed the relative contributions of frequency component elements of hemodynamic shear stress waveforms encountered in cardiovascular blood recirculating devices as to overall platelet activation over time. We demonstrated that high frequency oscillations are the major determinan...

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Pubblicato in:Sci Rep
Autori principali: Consolo, Filippo, Sheriff, Jawaad, Gorla, Silvia, Magri, Nicolò, Bluestein, Danny, Pappalardo, Federico, Slepian, Marvin J., Fiore, Gianfranco B., Redaelli, Alberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503983/
https://ncbi.nlm.nih.gov/pubmed/28694489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05130-5
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