Prothrombotic Activity of Cytokine-Activated Endothelial Cells and Shear-Activated Platelets in the Setting of Ventricular Assist Device Support

BACKGROUND: We systematically analyzed the synergistic effect of: i) cytokine-mediated inflammatory activation of endothelial cells (ECs), and ii) shear-mediated platelet activation (SMPA) as a potential contributory mechanism to intraventricular thrombus formation in the setting of Left Ventricular...

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Pubblicato in:J Heart Lung Transplant
Autori principali: Apostoli, Alice, Bianchi, Valentina, Bono, Nina, Dimasi, Annalisa, Ammann, Kaitlyn R, Roka-Moiia, Yana, Montisci, Andrea, Sheriff, Jawaad, Bluestein, Danny, Fiore, Gianfranco B, Pappalardo, Federico, Candiani, Gabriele, Redaelli, Alberto, Slepian, Marvin J, Consolo, Filippo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535357/
https://ncbi.nlm.nih.gov/pubmed/30846234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.healun.2019.02.009
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