Intrachromosomal amplification of chromosome 21 in Korean pediatric patients with B-cell precursor acute lymphoblastic leukemia in a single institution

BACKGROUND: Intrachromosomal amplification of chromosome 21 (iAMP21), defined as the presence of three or more RUNX1 signals on one marker chromosome, is a distinct cytogenetic subgroup of childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL) that is known to have a poor prognosis when t...

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Bibliographic Details
Published in:Blood Res
Main Authors: Yang, Mina, Yi, Eun Sang, Kim, Hee Jin, Yoo, Keon Hee, Koo, Hong Hoe, Kim, Sun-Hee
Format: Artigo
Language:Inglês
Published: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503886/
https://ncbi.nlm.nih.gov/pubmed/28698845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5045/br.2017.52.2.100
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