Frequency and Clinical Characteristics of Intrachromosomal Amplification of Chromosome 21 in Korean Childhood B-lineage Acute Lymphoblastic Leukemia

BACKGROUND: Intrachromosomal amplification of chromosome 21 (iAMP21) is known to be associated with poor prognosis in B-cell ALL (B-ALL). To determine the frequency and clinical characteristics of iAMP21 in Korean B-ALL patients, we performed FISH and multiplex ligation-dependent probe amplification...

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Detalhes bibliográficos
Publicado no:Ann Lab Med
Main Authors: Kim, Jieun, Lyu, Chuhl Joo, Shin, Saeam, Lee, Seung-Tae, Choi, Jong Rak
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society for Laboratory Medicine 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940492/
https://ncbi.nlm.nih.gov/pubmed/27374714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3343/alm.2016.36.5.475
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