Neuron-specific caveolin-1 overexpression improves motor function and preserves memory in mice subjected to brain trauma

Studies in vitro and in vivo demonstrate that membrane/lipid rafts and caveolin (Cav) organize progrowth receptors, and, when overexpressed specifically in neurons, Cav-1 augments neuronal signaling and growth and improves cognitive function in adult and aged mice; however, whether neuronal Cav-1 ov...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Egawa, Junji, Schilling, Jan M., Cui, Weihua, Posadas, Edmund, Sawada, Atsushi, Alas, Basheer, Zemljic-Harpf, Alice E., Fannon-Pavlich, McKenzie J., Mandyam, Chitra D., Roth, David M., Patel, Hemal H., Patel, Piyush M., Head, Brian P.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503707/
https://ncbi.nlm.nih.gov/pubmed/28450301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201601288RRR
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