A novel RON splice variant lacking exon 2 activates the PI3K/AKT pathway via PTEN phosphorylation in colorectal carcinoma cells

Abnormal expression of the Recepteur d'Origine Nantais (RON) receptor tyrosine kinase is accompanied by the generation of multiple splice or truncated variants, which mediate many critical cellular functions that contribute to tumor progression and metastasis. Here, we report a new RON splice v...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Ling, Yu, Kuang, Yeye, Chen, Lin-Lin, Lao, Wei-Feng, Zhu, Yao-Ru, Wang, Le-Qi, Wang, Da
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503598/
https://ncbi.nlm.nih.gov/pubmed/28388571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16603
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