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Roles of genetic variants in the PI3K/PTEN pathways in susceptibility to colorectal carcinoma and clinical outcomes treated with FOLFOX regimen

The genetic or abnormal activation of PI3K/PTEN signaling pathway play an important role with regard to disease progression in variety of human malignancies. Experimental and epidemiologic studies indicated that the genetic polymorphisms in the PTEN, PI3K genes are associated with cancer risk, yet l...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Lin, Lin, Zhang, Zhaoxu, Zhang, Wen, Wang, Lin, Wang, Jinwan
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680480/
https://ncbi.nlm.nih.gov/pubmed/26722535
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