A novel RON splice variant lacking exon 2 activates the PI3K/AKT pathway via PTEN phosphorylation in colorectal carcinoma cells

Abnormal expression of the Recepteur d'Origine Nantais (RON) receptor tyrosine kinase is accompanied by the generation of multiple splice or truncated variants, which mediate many critical cellular functions that contribute to tumor progression and metastasis. Here, we report a new RON splice v...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ling, Yu, Kuang, Yeye, Chen, Lin-Lin, Lao, Wei-Feng, Zhu, Yao-Ru, Wang, Le-Qi, Wang, Da
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503598/
https://ncbi.nlm.nih.gov/pubmed/28388571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16603
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