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TAZ induces lung cancer stem cell properties and tumorigenesis by up-regulating ALDH1A1

Recent studies suggest that lung cancer stem cells (CSCs) may play major roles in lung cancer. Therefore, identification of lung CSC drivers may provide promising targets for lung cancer. TAZ is a transcriptional co-activator and key downstream effector of the Hippo pathway, which plays critical rol...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yu, Jihang, Alharbi, Adel, Shan, Hongchao, Hao, Yawei, Snetsinger, Brooke, Rauh, Michael J., Yang, Xiaolong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503543/
https://ncbi.nlm.nih.gov/pubmed/28415606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16430
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