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TAZ induces lung cancer stem cell properties and tumorigenesis by up-regulating ALDH1A1

Recent studies suggest that lung cancer stem cells (CSCs) may play major roles in lung cancer. Therefore, identification of lung CSC drivers may provide promising targets for lung cancer. TAZ is a transcriptional co-activator and key downstream effector of the Hippo pathway, which plays critical rol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Yu, Jihang, Alharbi, Adel, Shan, Hongchao, Hao, Yawei, Snetsinger, Brooke, Rauh, Michael J., Yang, Xiaolong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503543/
https://ncbi.nlm.nih.gov/pubmed/28415606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16430
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