Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells

Human colon cancers express higher levels of NADPH oxidase 1 [NOX1] than adjacent normal epithelium. It has been suggested that reactive oxygen species [ROS] derived from NOX1 contribute to DNA damage and neoplastic transformation in the colon, particularly during chronic inflammatory stress. Howeve...

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Pubblicato in:Oncotarget
Autori principali: Liu, Han, Antony, Smitha, Roy, Krishnendu, Juhasz, Agnes, Wu, Yongzhong, Lu, Jiamo, Meitzler, Jennifer L., Jiang, Guojian, Polley, Eric, Doroshow, James H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Priority Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503519/
https://ncbi.nlm.nih.gov/pubmed/28498822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17494
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