Host-derived CD70 suppresses murine GVHD by limiting donor T cell expansion and effector function

Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative treatment for hematologic and immunologic diseases. However, graft-versus-host disease (GVHD) may develop when donor-derived T cells recognize and damage genetically distinct normal host tissues. In addition to T cell...

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Publicado no:J Immunol
Main Authors: Leigh, Nicholas D., O'Neill, Rachel E., Du, Wei, Chen, Chuan, Qiu, Jingxin, Ashwell, Jonathan D., McCarthy, Philip L., Chen, George L., Cao, Xuefang
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503479/
https://ncbi.nlm.nih.gov/pubmed/28550198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502181
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