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Dark Hydrazone Fluorescence Labeling Agents Enable Imaging of Cellular Aldehydic Load

Aldehydes are key intermediates in many cellular processes, from endogenous metabolic pathways like glycolysis to undesired exogenously induced processes such as lipid peroxidation and DNA interstrand cross-linking. Alkyl aldehydes are well documented to be cytotoxic, affecting the functions of DNA...

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Publicat a:ACS Chem Biol
Autors principals: Yuen, Lik Hang, Saxena, Nivedita S., Park, Hyun Shin, Weinberg, Kenneth, Kool, Eric T.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503141/
https://ncbi.nlm.nih.gov/pubmed/27326450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00269
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