Dual Tumor-Targeting Nanocarrier System for siRNA Delivery Based on pRNA and Modified Chitosan

Highly specific and efficient delivery of siRNA is still unsatisfactory. Herein, a dual tumor-targeting siRNA delivery system combining pRNA dimers with chitosan nanoparticles (CNPPs) was designed to improve the specificity and efficiency of siRNA delivery. In this dual delivery system, folate-conju...

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Detalles Bibliográficos
Publicado en:Mol Ther Nucleic Acids
Main Authors: Li, Lin, Hu, Xiaoqin, Zhang, Min, Ma, Siyu, Yu, Fanglin, Zhao, Shiqing, Liu, Nan, Wang, Zhiyuan, Wang, Yu, Guan, Hua, Pan, Xiujie, Gao, Yue, Zhang, Yue, Liu, Yan, Yang, Yang, Tang, Xuemei, Li, Mingyuan, Liu, Cheng, Li, Zhiping, Mei, Xingguo
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Gene & Cell Therapy 2017
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503097/
https://ncbi.nlm.nih.gov/pubmed/28918019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.06.014
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