CXCL12/CXCR4 signaling-mediated ERK1/2 activation in spinal cord contributes to the pathogenesis of postsurgical pain in rats

BACKGROUND: It has been demonstrated that upregulation of CXCL12 and CXCR4 in spinal cord involves in the pathogenesis of neuropathic, inflammatory, and cancer pain. However, whether CXCL12/CXCR4 signaling contributes to postsurgical pain remains unknown. The aim of the present study is to investiga...

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Veröffentlicht in:Mol Pain
Hauptverfasser: Xing, Fei, Kong, Cunlong, Bai, Liying, Qian, Junliang, Yuan, Jingjing, Li, Zhisong, Zhang, Wei, Xu, Ji-Tian
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502942/
https://ncbi.nlm.nih.gov/pubmed/28633557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806917718753
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