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CXCR4/CXCL12 hyperexpression plays a pivotal role in the pathogenesis of lupus
Among various surface molecules screened, CXCR4 was significantly up-regulated on monocytes, neutrophils, B-cell subsets, and plasma cells in multiple murine models of lupus with active nephritis, including B6.Sle1Yaa, BXSB, and MRL.lpr. TLR-mediated signaling and inflammatory cytokines accounted in...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2009
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946082/ https://ncbi.nlm.nih.gov/pubmed/19299746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0801920 |
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