CXCR4/CXCL12 hyperexpression plays a pivotal role in the pathogenesis of lupus

Among various surface molecules screened, CXCR4 was significantly up-regulated on monocytes, neutrophils, B-cell subsets, and plasma cells in multiple murine models of lupus with active nephritis, including B6.Sle1Yaa, BXSB, and MRL.lpr. TLR-mediated signaling and inflammatory cytokines accounted in...

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Autori principali: Wang, Andrew, Fairhurst, Anna-Marie, Tus, Katalin, Subramanian, Srividya, Liu, Yang, Lin, Fangming, Igarashi, Peter, Zhou, Xin J., Batteux, Frederic, Wong, Donald, Wakeland, Edward K., Mohan, Chandra
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946082/
https://ncbi.nlm.nih.gov/pubmed/19299746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0801920
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