Variation in the Zinc Finger of PRDM9 is Associated with the Absence of Recombination along Nondisjoined Chromosomes 21 of Maternal Origin

Variation in the zinc finger-binding domain (ZFBD) of the protein PR Domain-Containing Protein 9 (PRDM9) is associated with altered placement of recombination in the human genome. As both the absence and altered placement of recombination are observed among chromosomes 21 that nondisjoin, we genotyp...

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Detalhes bibliográficos
Publicado no:J Down Syndr Chromosom Abnorm
Main Authors: Oliver, Tiffany Renee, Middlebrooks, Candace, Harden, Ariel, Scott, Nyeisha, Johnson, Blair, Jones, Jillian, Walker, Christin, Wilkerson, Corinthia, Saffold, Sha-Hanna, Akinseye, Abisola, Smith, Tunde, Feingold, Eleanor, Sherman, Stephanie L
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502783/
https://ncbi.nlm.nih.gov/pubmed/28702511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2472-1115.1000115
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