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Tetrahydrobiopterin regulates monoamine neurotransmitter sulfonation

Monoamine neurotransmitters are among the hundreds of signaling small molecules whose target interactions are switched “on” and “off” via transfer of the sulfuryl-moiety (–SO(3)) from PAPS (3′-phosphoadenosine 5′-phosphosulfate) to the hydroxyls and amines of their scaffolds. These transfer reaction...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Cook, Ian, Wang, Ting, Leyh, Thomas S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502633/
https://ncbi.nlm.nih.gov/pubmed/28630292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704500114
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