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3′-Phosphoadenosine 5′-Phosphosulfate Allosterically Regulates Sulfotransferase Turnover

[Image: see text] Human cytosolic sulfotransferases (SULTs) regulate the activities of thousands of small molecules—metabolites, drugs, and other xenobiotics—via the transfer of the sulfuryl moiety (-SO(3)) from 3′-phosphoadenosine 5′-phosphosulfate (PAPS) to the hydroxyls and primary amines of acce...

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Publicado en:Biochemistry
Main Authors: Wang, Ting, Cook, Ian, Leyh, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230322/
https://ncbi.nlm.nih.gov/pubmed/25314023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501120p
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