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Regulation of Murine Hepatic Hydroxysteroid Sulfotransferase Expression in Hyposulfatemic Mice and in a Cell Model of 3′-Phosphoadenosine-5′-Phosphosulfate Deficiency

The cytosolic sulfotransferases (SULTs) catalyze the sulfate conjugation of nucleophilic substrates, and the cofactor for sulfonation, 3′-phosphoadenosine-5′-phosphosulfate (PAPS), is biosynthesized from sulfate and ATP. The phenotype of male knockout mice for the NaS1 sodium sulfate cotransporter i...

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Hlavní autoři: Barrett, Kathleen G., Fang, Hailin, Gargano, Mary D., Markovich, Daniel, Kocarek, Thomas A., Runge-Morris, Melissa
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716305/
https://ncbi.nlm.nih.gov/pubmed/23674610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.113.051912
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