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Isoform-specific therapeutic control of sulfonation in humans

The activities of hundreds, perhaps thousands, of metabolites are regulated by human cytosolic sulfotransferases (SULTs) – a 13-member family of disease relevant enzymes that catalyze transfer of the sulfuryl moiety (-SO(3)) from PAPS (3′-phosphoadenosine 5′-phosphosulfonate) to the hydroxyls and am...

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Publicat a:Biochem Pharmacol
Autors principals: Cook, Ian, Wang, Ting, Leyh, Thomas S.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625639/
https://ncbi.nlm.nih.gov/pubmed/30423313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2018.11.010
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